We can support your drug development program from the initial drug target discovery and validation. For later clinical trials, we can build databases providing drug sensitivity of gene variants to guide patient inclusion and novel treatment approaches.
For supporting counselling of families potentially at risk for hereditary genetic diseases, we can build disease relevant cell models to be used for testing if your observed gene variant is loss-of-function, and hence likely pathogenic.
We can support your drug development program from the initial drug target validation. For later clinical trials, we can build databases providing drug sensitivity of gene variants to guide patient inclusion.
For supporting medical chemistry optimisation, we can provide mutational scanning of your drug target to identify residuals that are required for the compound target interaction.